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Establishment and stability of the latent HIV-1 DNA reservoir

HIV-1 infection cannot be cured because the virus persists as integrated proviral DNA in long-lived cells despite years of suppressive antiretroviral therapy (ART). In a previous paper (Zanini et al, 2015) we documented HIV-1 evolution in 10 untreated patients. Here we characterize establishment, tu...

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Detalles Bibliográficos
Autores principales:	Brodin, Johanna, Zanini, Fabio, Thebo, Lina, Lanz, Christa, Bratt, Göran, Neher, Richard A, Albert, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201419/ https://www.ncbi.nlm.nih.gov/pubmed/27855060 http://dx.doi.org/10.7554/eLife.18889

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