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Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions

Host-directed therapies (HDTs) constitute promising alternatives to traditional therapy that directly targets the pathogen but is often hampered by pathogen resistance. HDT could represent a new treatment strategy for leishmaniasis, a neglected tropical disease caused by the obligate intracellular p...

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Detalles Bibliográficos
Autores principales: De Muylder, Géraldine, Vanhollebeke, Benoit, Caljon, Guy, Wolfe, Alan R., McKerrow, James, Dujardin, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201425/
https://www.ncbi.nlm.nih.gov/pubmed/28036391
http://dx.doi.org/10.1371/journal.pntd.0005234