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Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions
Host-directed therapies (HDTs) constitute promising alternatives to traditional therapy that directly targets the pathogen but is often hampered by pathogen resistance. HDT could represent a new treatment strategy for leishmaniasis, a neglected tropical disease caused by the obligate intracellular p...
Autores principales: | De Muylder, Géraldine, Vanhollebeke, Benoit, Caljon, Guy, Wolfe, Alan R., McKerrow, James, Dujardin, Jean-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201425/ https://www.ncbi.nlm.nih.gov/pubmed/28036391 http://dx.doi.org/10.1371/journal.pntd.0005234 |
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