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Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes

Studies of Leishmania donovani have shown that both ornithine decarboxylase and spermidine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote proliferation and required for maximum infection in mice. However, the importance of arginase (ARG), the first enzyme...

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Detalles Bibliográficos
Autores principales:	Boitz, Jan M., Gilroy, Caslin A., Olenyik, Tamara D., Paradis, Dustin, Perdeh, Jasmine, Dearman, Kristie, Davis, Madison J., Yates, Phillip A., Li, Yuexin, Riscoe, Michael K., Ullman, Buddy, Roberts, Sigrid C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203656/ https://www.ncbi.nlm.nih.gov/pubmed/27795357 http://dx.doi.org/10.1128/IAI.00554-16

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