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Newcastle disease virus degrades HIF-1α through proteasomal pathways independent of VHL and p53

Newcastle disease virus (NDV) is a candidate agent for oncolytic virotherapy. Despite its potential, the exact mechanism of its oncolysis is still not known. Recently, we reported that NDV exhibited an increased oncolytic activity in hypoxic cancer cells. These types of cells negatively affect thera...

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Detalles Bibliográficos
Autores principales:	Abd-Aziz, Noraini, Stanbridge, Eric J., Shafee, Norazizah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2016
Materias:	Standard
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203671/ https://www.ncbi.nlm.nih.gov/pubmed/27902314 http://dx.doi.org/10.1099/jgv.0.000623

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