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The conserved N-terminus of human rhinovirus capsid protein VP4 contains membrane pore-forming activity and is a target for neutralizing antibodies

Human rhinovirus is the causative agent of the common cold and belongs to the non-enveloped picornavirus family. A trigger such as receptor binding or low pH initiates conformational changes in the capsid that allow the virus to attach to membranes and form a pore for the translocation of viral RNA...

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Detalles Bibliográficos
Autores principales: Panjwani, Anusha, Asfor, Amin S., Tuthill, Tobias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203672/
https://www.ncbi.nlm.nih.gov/pubmed/27902347
http://dx.doi.org/10.1099/jgv.0.000629