The incredible complexity of RNA splicing

Alternative splice isoforms are common and important and have been shown to impact many human diseases. A new study by Nellore et al. offers a comprehensive study of splice junctions in humans by re-analyzing over 21,500 public human RNA sequencing datasets.

Detalles Bibliográficos
Autores principales: Robert, Christelle, Watson, Mick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203710/
https://www.ncbi.nlm.nih.gov/pubmed/28038679
http://dx.doi.org/10.1186/s13059-016-1121-y
Descripción
Sumario:Alternative splice isoforms are common and important and have been shown to impact many human diseases. A new study by Nellore et al. offers a comprehensive study of splice junctions in humans by re-analyzing over 21,500 public human RNA sequencing datasets.

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