Grafted c-kit(+)/SSEA1(−) eye-wall progenitor cells delay retinal degeneration in mice by regulating neural plasticity and forming new graft-to-host synapses

BACKGROUND: Despite diverse pathogenesis, the common pathological change observed in age-related macular degeneration and in most hereditary retinal degeneration (RD) diseases is photoreceptor loss. Photoreceptor replacement by cell transplantation may be a feasible treatment for RD. The major obsta...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Chen, Zehua, Li, Zhengya, Zhao, Chen, Zeng, Yuxiao, Zou, Ting, Fu, Caiyun, Liu, Xiaoli, Xu, Haiwei, Yin, Zheng Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203726/
https://www.ncbi.nlm.nih.gov/pubmed/28038685
http://dx.doi.org/10.1186/s13287-016-0451-8

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