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MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro

BACKGROUND: MicroRNAs (miRNAs) are small regulatory molecules that cause translational repression by base pairing with target mRNAs. Cumulative evidence suggests that changes in miRNA expression may in part underlie the pathophysiology and treatment of neuropsychiatric disorders, including major dep...

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Detalles Bibliográficos
Autores principales: Wei, Ya Bin, Melas, Philippe A., Villaescusa, J. Carlos, Liu, Jia Jia, Xu, Ning, Christiansen, Søren Hofman, Elbrønd-Bek, Heidi, Woldbye, David Paul Drucker, Wegener, Gregers, Mathé, Aleksander A., Lavebratt, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203758/
https://www.ncbi.nlm.nih.gov/pubmed/27507301
http://dx.doi.org/10.1093/ijnp/pyw069