RAG Recombinase as a Selective Pressure for Genome Evolution

The RAG recombinase is a domesticated transposable element co-opted in jawed vertebrates to drive the process of the so-called V(D)J recombination, which is the hallmark of the adaptive immune system to produce antigen receptors. RAG targets, namely, the Recombination Signal Sequences (RSS), are rat...

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Detalles Bibliográficos
Autores principales: Passagem-Santos, D., Bonnet, M., Sobral, D., Trancoso, I., Silva, J.G., Barreto, V.M., Athanasiadis, A., Demengeot, J., Pereira-Leal, J.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203794/
https://www.ncbi.nlm.nih.gov/pubmed/27979968
http://dx.doi.org/10.1093/gbe/evw261

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