Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar

Cryptococcal meningoencephalitis is considered rare in HIV-negative individuals. In Madagascar, the epidemiology of cryptococcosis has not yet been well described, neither in immunocompetent nor in immunocompromised patients. We report here the first Malagasy detailed case of cryptococcal meningoenc...

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Autores principales: Raberahona, Mihaja, Rakotoarivelo, Rivonirina A., Randriamampionona, Njary, Rakotomalala, Angelot F., Razafinambinintsoa, Tiana, Bénet, Thomas, Vanhems, Philippe, Randria, Mamy J. D. D., Cornet, Muriel, Rakoto-Andrianarivelo, Mala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203877/
https://www.ncbi.nlm.nih.gov/pubmed/28078149
http://dx.doi.org/10.1155/2016/3492504
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author Raberahona, Mihaja
Rakotoarivelo, Rivonirina A.
Randriamampionona, Njary
Rakotomalala, Angelot F.
Razafinambinintsoa, Tiana
Bénet, Thomas
Vanhems, Philippe
Randria, Mamy J. D. D.
Cornet, Muriel
Rakoto-Andrianarivelo, Mala
author_facet Raberahona, Mihaja
Rakotoarivelo, Rivonirina A.
Randriamampionona, Njary
Rakotomalala, Angelot F.
Razafinambinintsoa, Tiana
Bénet, Thomas
Vanhems, Philippe
Randria, Mamy J. D. D.
Cornet, Muriel
Rakoto-Andrianarivelo, Mala
author_sort Raberahona, Mihaja
collection PubMed
description Cryptococcal meningoencephalitis is considered rare in HIV-negative individuals. In Madagascar, the epidemiology of cryptococcosis has not yet been well described, neither in immunocompetent nor in immunocompromised patients. We report here the first Malagasy detailed case of cryptococcal meningoencephalitis in a non-HIV immunocompromised adult patient carrying a low fluconazole susceptibility isolate. We emphasize the importance of early and accurate diagnosis to meet the challenges of managing cryptococcosis in developing countries.
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spelling pubmed-52038772017-01-11 Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar Raberahona, Mihaja Rakotoarivelo, Rivonirina A. Randriamampionona, Njary Rakotomalala, Angelot F. Razafinambinintsoa, Tiana Bénet, Thomas Vanhems, Philippe Randria, Mamy J. D. D. Cornet, Muriel Rakoto-Andrianarivelo, Mala Case Rep Infect Dis Case Report Cryptococcal meningoencephalitis is considered rare in HIV-negative individuals. In Madagascar, the epidemiology of cryptococcosis has not yet been well described, neither in immunocompetent nor in immunocompromised patients. We report here the first Malagasy detailed case of cryptococcal meningoencephalitis in a non-HIV immunocompromised adult patient carrying a low fluconazole susceptibility isolate. We emphasize the importance of early and accurate diagnosis to meet the challenges of managing cryptococcosis in developing countries. Hindawi Publishing Corporation 2016 2016-12-18 /pmc/articles/PMC5203877/ /pubmed/28078149 http://dx.doi.org/10.1155/2016/3492504 Text en Copyright © 2016 Mihaja Raberahona et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Raberahona, Mihaja
Rakotoarivelo, Rivonirina A.
Randriamampionona, Njary
Rakotomalala, Angelot F.
Razafinambinintsoa, Tiana
Bénet, Thomas
Vanhems, Philippe
Randria, Mamy J. D. D.
Cornet, Muriel
Rakoto-Andrianarivelo, Mala
Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title_full Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title_fullStr Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title_full_unstemmed Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title_short Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
title_sort rapid fatal outcome of cryptococcal meningoencephalitis in a non-hiv immunocompromised patient with a low fluconazole susceptibility isolate: a case report from madagascar
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203877/
https://www.ncbi.nlm.nih.gov/pubmed/28078149
http://dx.doi.org/10.1155/2016/3492504
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