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Noncanonical IFN Signaling: Mechanistic Linkage of Genetic and Epigenetic Events
The canonical model of cytokine signaling via the JAK/STAT pathway dominates our view of signal transduction but provides no insight into the significance of the simultaneous presence of activated JAKs and STATs in the nucleus of cells treated with cytokines. Such a mechanistic shortcoming challenge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203919/ https://www.ncbi.nlm.nih.gov/pubmed/28077919 http://dx.doi.org/10.1155/2016/9564814 |