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A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient
Varicella zoster virus (VZV) is a human neurotropic alphaherpesvirus that causes chickenpox (varicella) in children. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. He...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204014/ https://www.ncbi.nlm.nih.gov/pubmed/27883372 http://dx.doi.org/10.3947/ic.2016.48.4.334 |
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author | Lee, Jeong Eun Lee, Shinwon Kim, Kye-Hyung Jang, Hee Ryeong Park, Young Joo Kang, Jin Suk Han, Sung Yong Lee, Sun Hee |
author_facet | Lee, Jeong Eun Lee, Shinwon Kim, Kye-Hyung Jang, Hee Ryeong Park, Young Joo Kang, Jin Suk Han, Sung Yong Lee, Sun Hee |
author_sort | Lee, Jeong Eun |
collection | PubMed |
description | Varicella zoster virus (VZV) is a human neurotropic alphaherpesvirus that causes chickenpox (varicella) in children. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. Herein, we report a case of transverse myelitis caused by VZV in an immunocompetent older patient, and confirmed this case by polymerase chain reaction. A 79-year-old woman visited our service with complaints of weakness in the right lower leg, generalized vesicular eruptions, and throbbing pain in the right flank for ten days. Spine MRI showed transverse myelitis in the thoracic spine at level T4–T11. The patient was treated with acyclovir and her neurological functions improved, except for sensory impairment below level T10. For older patients, early and aggressive antiviral treatment against VZV may be necessary even though these patients are immunocompetent. |
format | Online Article Text |
id | pubmed-5204014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Society of Infectious Diseases and Korean Society for Chemotherapy |
record_format | MEDLINE/PubMed |
spelling | pubmed-52040142017-01-04 A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient Lee, Jeong Eun Lee, Shinwon Kim, Kye-Hyung Jang, Hee Ryeong Park, Young Joo Kang, Jin Suk Han, Sung Yong Lee, Sun Hee Infect Chemother Case Report Varicella zoster virus (VZV) is a human neurotropic alphaherpesvirus that causes chickenpox (varicella) in children. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. Herein, we report a case of transverse myelitis caused by VZV in an immunocompetent older patient, and confirmed this case by polymerase chain reaction. A 79-year-old woman visited our service with complaints of weakness in the right lower leg, generalized vesicular eruptions, and throbbing pain in the right flank for ten days. Spine MRI showed transverse myelitis in the thoracic spine at level T4–T11. The patient was treated with acyclovir and her neurological functions improved, except for sensory impairment below level T10. For older patients, early and aggressive antiviral treatment against VZV may be necessary even though these patients are immunocompetent. The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2016-12 2016-11-11 /pmc/articles/PMC5204014/ /pubmed/27883372 http://dx.doi.org/10.3947/ic.2016.48.4.334 Text en Copyright © 2016 by The Korean Society of Infectious Diseases and Korean Society for Chemotherapy http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lee, Jeong Eun Lee, Shinwon Kim, Kye-Hyung Jang, Hee Ryeong Park, Young Joo Kang, Jin Suk Han, Sung Yong Lee, Sun Hee A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title | A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title_full | A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title_fullStr | A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title_full_unstemmed | A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title_short | A Case of Transverse Myelitis Caused by Varicella Zoster Virus in an Immunocompetent Older Patient |
title_sort | case of transverse myelitis caused by varicella zoster virus in an immunocompetent older patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204014/ https://www.ncbi.nlm.nih.gov/pubmed/27883372 http://dx.doi.org/10.3947/ic.2016.48.4.334 |
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