MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells

Type 1 diabetes (T1D) is an autoimmune disease leading to β-cell destruction. MicroRNAs (miRNAs) are small noncoding RNAs that control gene expression and organ formation. They participate in the pathogenesis of several autoimmune diseases, but the nature of miRNAs contributing to β-cell death in T1...

Descripción completa

Detalles Bibliográficos
Autores principales: Grieco, Fabio Arturo, Sebastiani, Guido, Juan-Mateu, Jonas, Villate, Olatz, Marroqui, Laura, Ladrière, Laurence, Tugay, Ksenya, Regazzi, Romano, Bugliani, Marco, Marchetti, Piero, Dotta, Francesco, Eizirik, Décio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204315/
https://www.ncbi.nlm.nih.gov/pubmed/27737950
http://dx.doi.org/10.2337/db16-0592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204315/
https://www.ncbi.nlm.nih.gov/pubmed/27737950
http://dx.doi.org/10.2337/db16-0592

Ejemplares similares