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Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
Overcoming the immune response to establish durable immune tolerance in type 1 diabetes remains a substantial challenge. The ongoing effector immune response involves numerous immune cell types but is ultimately orchestrated and sustained by the hematopoietic stem cell (HSC) niche. We therefore hypo...
Autores principales: | Stocks, Blair T., Thomas, Analise B., Elizer, Sydney K., Zhu, Yuantee, Marshall, Andrew F., Wilson, Christopher S., Moore, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204317/ https://www.ncbi.nlm.nih.gov/pubmed/27797908 http://dx.doi.org/10.2337/db16-0444 |
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