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Identification of complex genomic rearrangements in cancers using CouGaR

The genomic alterations associated with cancers are numerous and varied, involving both isolated and large-scale complex genomic rearrangements (CGRs). Although the underlying mechanisms are not well understood, CGRs have been implicated in tumorigenesis. Here, we introduce CouGaR, a novel method fo...

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Detalles Bibliográficos
Autores principales: Dzamba, Misko, Ramani, Arun K., Buczkowicz, Pawel, Jiang, Yue, Yu, Man, Hawkins, Cynthia, Brudno, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204335/
https://www.ncbi.nlm.nih.gov/pubmed/27986820
http://dx.doi.org/10.1101/gr.211201.116