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Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

While long intergenic noncoding RNAs (lincRNAs) and mRNAs share similar biogenesis pathways, these transcript classes differ in many regards. LincRNAs are less evolutionarily conserved, less abundant, and more tissue-specific, suggesting that their pre- and post-transcriptional regulation is differe...

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Detalles Bibliográficos
Autores principales:	Melé, Marta, Mattioli, Kaia, Mallard, William, Shechner, David M., Gerhardinger, Chiara, Rinn, John L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204342/ https://www.ncbi.nlm.nih.gov/pubmed/27927715 http://dx.doi.org/10.1101/gr.214205.116

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