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The RNA-induced transcriptional silencing complex targets chromatin exclusively via interacting with nascent transcripts
Small RNAs regulate chromatin modification and transcriptional gene silencing across the eukaryotic kingdom. Although these processes have been well studied, fundamental mechanistic aspects remain obscure. Specifically, it is unclear exactly how small RNA-loaded Argonaute protein complexes target ch...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204350/ https://www.ncbi.nlm.nih.gov/pubmed/27941123 http://dx.doi.org/10.1101/gad.292599.116 |