A phosphorylation–deubiquitination cascade regulates the BRCA2–RAD51 axis in homologous recombination

Homologous recombination (HR) is one of the major DNA double-strand break (DSB) repair pathways in mammalian cells. Defects in HR trigger genomic instability and result in cancer predisposition. The defining step of HR is homologous strand exchange directed by the protein RAD51, which is recruited t...

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Detalles Bibliográficos
Autores principales: Luo, Kuntian, Li, Lei, Li, Yunhui, Wu, Chenming, Yin, Yujiao, Chen, Yuping, Deng, Min, Nowsheen, Somaira, Yuan, Jian, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204351/
https://www.ncbi.nlm.nih.gov/pubmed/27941124
http://dx.doi.org/10.1101/gad.289439.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204351/
https://www.ncbi.nlm.nih.gov/pubmed/27941124
http://dx.doi.org/10.1101/gad.289439.116

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