An ensemble of regulatory elements controls Runx3 spatiotemporal expression in subsets of dorsal root ganglia proprioceptive neurons

The Runx3 transcription factor is essential for development and diversification of the dorsal root ganglia (DRGs) TrkC sensory neurons. In Runx3-deficient mice, developing TrkC neurons fail to extend central and peripheral afferents, leading to cell death and disruption of the stretch reflex circuit...

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Detalles Bibliográficos
Autores principales: Appel, Elena, Weissmann, Sarit, Salzberg, Yehuda, Orlovsky, Kira, Negreanu, Varda, Tsoory, Michael, Raanan, Calanit, Feldmesser, Ester, Bernstein, Yael, Wolstein, Orit, Levanon, Ditsa, Groner, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204353/
https://www.ncbi.nlm.nih.gov/pubmed/28007784
http://dx.doi.org/10.1101/gad.291484.116

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