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Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis

PURPOSE: Optic neuritis, inflammation of the optic nerve, is experienced by most patients with multiple sclerosis (MS) and is typically characterized by episodes of acute, monocular vision loss. These episodes of inflammation can lead to damage or degeneration of the retinal ganglion cells (RGCs), t...

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Detalles Bibliográficos
Autores principales: Larabee, Chelsea M., Desai, Shruti, Agasing, Agnieshka, Georgescu, Constantin, Wren, Jonathan D., Axtell, Robert C., Plafker, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204460/
https://www.ncbi.nlm.nih.gov/pubmed/28050123