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Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function
Cefepime-induced encephalopathy including nonconvulsive status epilepticus has been known to develop in the patients with renal impairment. However, we report a 74-year-old woman with normal renal function who developed stuporous mental status during cefepime administration. Electroencephalogram (EE...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Epilepsy Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206107/ https://www.ncbi.nlm.nih.gov/pubmed/28101482 http://dx.doi.org/10.14581/jer.16018 |
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author | Park, Hyeon-Mi Noh, Young Yang, Ji Won Shin, Dong Hoon Lee, Yeong-Bae |
author_facet | Park, Hyeon-Mi Noh, Young Yang, Ji Won Shin, Dong Hoon Lee, Yeong-Bae |
author_sort | Park, Hyeon-Mi |
collection | PubMed |
description | Cefepime-induced encephalopathy including nonconvulsive status epilepticus has been known to develop in the patients with renal impairment. However, we report a 74-year-old woman with normal renal function who developed stuporous mental status during cefepime administration. Electroencephalogram (EEG) revealed 2 Hz rhythmic sharp-and-waves continuously, which suggested nonconvulsive status epilepticus (NCSE). After cefepime discontinuation, clinical symptoms recovered gradually and EEG findings showed only background slowing without epileptiform discharges. Cefepime-induced NCSE could be developed even in the patients with normal renal function, when they are elderly. Therefore, clinicians should be aware of the possibility of cefepime-induced NCSE when prescribing cefepime even to the patients with normal renal function. |
format | Online Article Text |
id | pubmed-5206107 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Korean Epilepsy Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-52061072017-01-18 Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function Park, Hyeon-Mi Noh, Young Yang, Ji Won Shin, Dong Hoon Lee, Yeong-Bae J Epilepsy Res Case Report Cefepime-induced encephalopathy including nonconvulsive status epilepticus has been known to develop in the patients with renal impairment. However, we report a 74-year-old woman with normal renal function who developed stuporous mental status during cefepime administration. Electroencephalogram (EEG) revealed 2 Hz rhythmic sharp-and-waves continuously, which suggested nonconvulsive status epilepticus (NCSE). After cefepime discontinuation, clinical symptoms recovered gradually and EEG findings showed only background slowing without epileptiform discharges. Cefepime-induced NCSE could be developed even in the patients with normal renal function, when they are elderly. Therefore, clinicians should be aware of the possibility of cefepime-induced NCSE when prescribing cefepime even to the patients with normal renal function. Korean Epilepsy Society 2016-12-31 /pmc/articles/PMC5206107/ /pubmed/28101482 http://dx.doi.org/10.14581/jer.16018 Text en Copyright © 2016 Korean Epilepsy Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Park, Hyeon-Mi Noh, Young Yang, Ji Won Shin, Dong Hoon Lee, Yeong-Bae Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title | Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title_full | Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title_fullStr | Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title_full_unstemmed | Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title_short | Cefepime-Induced Non-Convulsive Status Epilepticus in a Patient with Normal Renal Function |
title_sort | cefepime-induced non-convulsive status epilepticus in a patient with normal renal function |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206107/ https://www.ncbi.nlm.nih.gov/pubmed/28101482 http://dx.doi.org/10.14581/jer.16018 |
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