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Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations

In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifoliu...

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Autores principales: Andor, Bogdan, Danciu, Corina, Alexa, Ersilia, Zupko, Istvan, Hogea, Elena, Cioca, Andreea, Coricovac, Dorina, Pinzaru, Iulia, Pătrașcu, Jenel Marian, Mioc, Marius, Cristina, Romeo Teodor, Soica, Codruta, Dehelean, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206418/
https://www.ncbi.nlm.nih.gov/pubmed/28090213
http://dx.doi.org/10.1155/2016/7638542
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author Andor, Bogdan
Danciu, Corina
Alexa, Ersilia
Zupko, Istvan
Hogea, Elena
Cioca, Andreea
Coricovac, Dorina
Pinzaru, Iulia
Pătrașcu, Jenel Marian
Mioc, Marius
Cristina, Romeo Teodor
Soica, Codruta
Dehelean, Cristina
author_facet Andor, Bogdan
Danciu, Corina
Alexa, Ersilia
Zupko, Istvan
Hogea, Elena
Cioca, Andreea
Coricovac, Dorina
Pinzaru, Iulia
Pătrașcu, Jenel Marian
Mioc, Marius
Cristina, Romeo Teodor
Soica, Codruta
Dehelean, Cristina
author_sort Andor, Bogdan
collection PubMed
description In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds.
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spelling pubmed-52064182017-01-15 Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations Andor, Bogdan Danciu, Corina Alexa, Ersilia Zupko, Istvan Hogea, Elena Cioca, Andreea Coricovac, Dorina Pinzaru, Iulia Pătrașcu, Jenel Marian Mioc, Marius Cristina, Romeo Teodor Soica, Codruta Dehelean, Cristina Evid Based Complement Alternat Med Research Article In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds. Hindawi Publishing Corporation 2016 2016-12-20 /pmc/articles/PMC5206418/ /pubmed/28090213 http://dx.doi.org/10.1155/2016/7638542 Text en Copyright © 2016 Bogdan Andor et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Andor, Bogdan
Danciu, Corina
Alexa, Ersilia
Zupko, Istvan
Hogea, Elena
Cioca, Andreea
Coricovac, Dorina
Pinzaru, Iulia
Pătrașcu, Jenel Marian
Mioc, Marius
Cristina, Romeo Teodor
Soica, Codruta
Dehelean, Cristina
Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title_full Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title_fullStr Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title_full_unstemmed Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title_short Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations
title_sort germinated and ungerminated seeds extract from two lupinus species: biological compounds characterization and in vitro and in vivo evaluations
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206418/
https://www.ncbi.nlm.nih.gov/pubmed/28090213
http://dx.doi.org/10.1155/2016/7638542
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