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Hyaluromycin, a Novel Hyaluronidase Inhibitor, Attenuates Pancreatic Cancer Cell Migration and Proliferation
Pancreatic ductal adenocarcinoma (PDAC) is characterized by accelerated production and degradation of hyaluronan (HA), a major component of extracellular matrix involved in the malignant phenotype of cancer. In particular, increased hyaluronidase (HYAL) activity plays a critical role in cancer progr...
Autores principales: | Kohi, Shiro, Sato, Norihiro, Koga, Atsuhiro, Hirata, Keiji, Harunari, Enjuro, Igarashi, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206452/ https://www.ncbi.nlm.nih.gov/pubmed/28096814 http://dx.doi.org/10.1155/2016/9063087 |
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