Uninephrectomized High-Fat-Fed Nicotinamide-Streptozotocin-Induced Diabetic Rats: A Model for the Investigation of Diabetic Nephropathy in Type 2 Diabetes

Type 2 diabetes (DM2) could be reproduced in rats with alimentary obesity by using low doses of streptozotocin (LD-STZ) as well as STZ in high doses with preliminary nicotinamide (NA) administration. However, STZ could induce tubulotoxicity. Aim. To develop rat model of DN in NA-STZ-induced DM2 and...

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Detalles Bibliográficos
Autores principales: Bayrasheva, Valentina K., Babenko, Alina Yu., Dobronravov, Vladimir A., Dmitriev, Yuri V., Chefu, Svetlana G., Pchelin, Ivan Yu., Ivanova, Alexandra N., Bairamov, Alekber A., Alexeyeva, Nina P., Shatalov, Ivan S., Grineva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206480/
https://www.ncbi.nlm.nih.gov/pubmed/28090542
http://dx.doi.org/10.1155/2016/8317850

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