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Batch effects and the effective design of single-cell gene expression studies

Single-cell RNA sequencing (scRNA-seq) can be used to characterize variation in gene expression levels at high resolution. However, the sources of experimental noise in scRNA-seq are not yet well understood. We investigated the technical variation associated with sample processing using the single-c...

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Detalles Bibliográficos
Autores principales:	Tung, Po-Yuan, Blischak, John D., Hsiao, Chiaowen Joyce, Knowles, David A., Burnett, Jonathan E., Pritchard, Jonathan K., Gilad, Yoav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206706/ https://www.ncbi.nlm.nih.gov/pubmed/28045081 http://dx.doi.org/10.1038/srep39921

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