Targeted RNA-Seq profiling of splicing pattern in the DMD gene: exons are mostly constitutively spliced in human skeletal muscle

We have analysed the splicing pattern of the human Duchenne Muscular Dystrophy (DMD) NB transcript in normal skeletal muscle. To achieve depth of coverage required for the analysis of this lowly expressed gene in muscle, we designed a targeted RNA-Seq procedure that combines amplification of the ful...

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Detalles Bibliográficos
Autores principales: Bougé, Anne-Laure, Murauer, Eva, Beyne, Emmanuelle, Miro, Julie, Varilh, Jessica, Taulan, Magali, Koenig, Michel, Claustres, Mireille, Tuffery-Giraud, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206723/
https://www.ncbi.nlm.nih.gov/pubmed/28045018
http://dx.doi.org/10.1038/srep39094

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