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Protective effects of intercalated disk protein afadin on chronic pressure overload-induced myocardial damage

Adhesive intercellular connections at cardiomyocyte intercalated disks (IDs) support contractile force and maintain structural integrity of the heart muscle. Disturbances of the proteins at IDs deteriorate cardiac function and morphology. An adaptor protein afadin, one of the components of adherens...

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Detalles Bibliográficos
Autores principales: Zankov, Dimitar P., Shimizu, Akio, Tanaka-Okamoto, Miki, Miyoshi, Jun, Ogita, Hisakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206728/
https://www.ncbi.nlm.nih.gov/pubmed/28045017
http://dx.doi.org/10.1038/srep39335