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Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages

As members of bromodomain and extra-terminal motif protein family, bromodomain-containing proteins regulate a wide range of biological processes including protein scaffolding, mitosis, cell cycle progression and transcriptional regulation. The function of these bromodomain proteins (Brds) in innate...

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Detalles Bibliográficos
Autores principales: Ren, Wenhui, Wang, Chunmei, Wang, Qinlan, Zhao, Dezhi, Zhao, Kai, Sun, Donghao, Liu, Xingguang, Han, Chaofeng, Hou, Jin, Li, Xia, Zhang, Qian, Cao, Xuetao, Li, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206742/
https://www.ncbi.nlm.nih.gov/pubmed/28045112
http://dx.doi.org/10.1038/srep39986

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