Mechanical stress activates NMDA receptors in the absence of agonists

While studying the physiological response of primary rat astrocytes to fluid shear stress in a model of traumatic brain injury (TBI), we found that shear stress induced Ca(2+) entry. The influx was inhibited by MK-801, a specific pore blocker of N-Methyl-D-aspartic acid receptor (NMDAR) channels, an...

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Detalles Bibliográficos
Autores principales: Maneshi, Mohammad Mehdi, Maki, Bruce, Gnanasambandam, Radhakrishnan, Belin, Sophie, Popescu, Gabriela K., Sachs, Frederick, Hua, Susan Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206744/
https://www.ncbi.nlm.nih.gov/pubmed/28045032
http://dx.doi.org/10.1038/srep39610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206744/
https://www.ncbi.nlm.nih.gov/pubmed/28045032
http://dx.doi.org/10.1038/srep39610

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