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The Ribosome Restrains Molten Globule Formation in Stalled Nascent Flavodoxin

Folding of proteins usually involves intermediates, of which an important type is the molten globule (MG). MGs are ensembles of interconverting conformers that contain (non-)native secondary structure and lack the tightly packed tertiary structure of natively folded globular proteins. Whereas MGs of...

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Detalles Bibliográficos
Autores principales: Houwman, Joseline A., André, Estelle, Westphal, Adrie H., van Berkel, Willem J. H., van Mierlo, Carlo P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207065/
https://www.ncbi.nlm.nih.gov/pubmed/27784783
http://dx.doi.org/10.1074/jbc.M116.756205