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Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation

Clostridium difficile is the principal cause of nosocomial infectious diarrhea worldwide. The pathogen modifies its flagellin with either a type A or type B O-linked glycosylation system, which has a contributory role in pathogenesis. We study the functional role of glycosyltransferases modifying ty...

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Detalles Bibliográficos
Autores principales:	Valiente, Esmeralda, Bouché, Laura, Hitchen, Paul, Faulds-Pain, Alexandra, Songane, Mario, Dawson, Lisa F., Donahue, Elizabeth, Stabler, Richard A., Panico, Maria, Morris, Howard R., Bajaj-Elliott, Mona, Logan, Susan M., Dell, Anne, Wren, Brendan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207246/ https://www.ncbi.nlm.nih.gov/pubmed/27703012 http://dx.doi.org/10.1074/jbc.M116.749523

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