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Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos
Nanos proteins repress the expression of target mRNAs by recruiting effector complexes through non‐conserved N‐terminal regions. In vertebrates, Nanos proteins interact with the NOT1 subunit of the CCR4–NOT effector complex through a NOT1 interacting motif (NIM), which is absent in Nanos orthologs f...
Autores principales: | Raisch, Tobias, Bhandari, Dipankar, Sabath, Kevin, Helms, Sigrun, Valkov, Eugene, Weichenrieder, Oliver, Izaurralde, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207322/ https://www.ncbi.nlm.nih.gov/pubmed/26968986 http://dx.doi.org/10.15252/embj.201593634 |
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