Cargando…
A novel role for the 3′-5′ exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth
In a complex organism, cell proliferation and apoptosis need to be precisely controlled in order for tissues to develop correctly. Excessive cell proliferation can lead to diseases such as cancer. We have shown that the exoribonuclease Dis3L2 is required for the correct regulation of proliferation i...
Autores principales: | Towler, Benjamin P., Jones, Christopher I., Harper, Kirsty L., Waldron, Joseph A., Newbury, Sarah F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207379/ https://www.ncbi.nlm.nih.gov/pubmed/27630034 http://dx.doi.org/10.1080/15476286.2016.1232238 |
Ejemplares similares
-
The 3'-5' exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs
por: Towler, Benjamin P, et al.
Publicado: (2015) -
The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease
por: Robinson, Sophie R., et al.
Publicado: (2015) -
Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism
por: Towler, Benjamin P., et al.
Publicado: (2020) -
Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs
por: Ustianenko, Dmytro, et al.
Publicado: (2013) -
The 5′-3′ exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277–3p in Drosophila wing imaginal discs
por: Jones, Christopher I, et al.
Publicado: (2013)