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In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies

Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotide sequences that bind to a specific target molecule with high affinity and specificity through their ability to adopt 3-dimensional structure in solution. Aptamers have huge potential as targeted therapeutics, diagnostics, delivery a...

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Detalles Bibliográficos
Autores principales:	Lipi, Farhana, Chen, Suxiang, Chakravarthy, Madhuri, Rakesh, Shilpa, Veedu, Rakesh N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207382/ https://www.ncbi.nlm.nih.gov/pubmed/27715478 http://dx.doi.org/10.1080/15476286.2016.1236173

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