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Nickel-catalyzed enantioselective arylation of pyridine

We report an enantioselective Ni-catalyzed cross coupling of arylzinc reagents with pyridinium ions formed in situ from pyridine and a chloroformate. This reaction provides enantioenriched 2-aryl-1,2-dihydropyridine products that can be elaborated to numerous piperidine derivatives with little or no...

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Detalles Bibliográficos
Autores principales:	Lutz, J. Patrick, Chau, Stephen T., Doyle, Abigail G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207490/ https://www.ncbi.nlm.nih.gov/pubmed/28058106 http://dx.doi.org/10.1039/c6sc00702c

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