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The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa

Streptococcus suis infects pigs worldwide and may be zoonotically transmitted to humans with a mortality rate of up to 20%. S. suis has been shown to develop in vitro resistance to the two leading drugs of choice, penicillin and gentamicin. Because of this, we have pursued an alternative therapy to...

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Detalles Bibliográficos
Autores principales: Gilmer, Daniel B., Schmitz, Jonathan E., Thandar, Mya, Euler, Chad W., Fischetti, Vincent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207509/
https://www.ncbi.nlm.nih.gov/pubmed/28046082
http://dx.doi.org/10.1371/journal.pone.0169180