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Extremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational Spectrum
The characterization of mutational spectra is usually carried out in one of three ways–by direct observation through mutation accumulation (MA) experiments, through parent-offspring sequencing, or by indirect inference from sequence data. Direct observations of spontaneous mutations with MA experime...
Autores principales: | Zhu, Yuan O., Sherlock, Gavin, Petrov, Dmitri A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207638/ https://www.ncbi.nlm.nih.gov/pubmed/28046117 http://dx.doi.org/10.1371/journal.pgen.1006455 |
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