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Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling Age

Neonatal foals respond poorly to conventional vaccines. These vaccines typically target T-helper (Th) cell dependent B-cell activation. However, Th2-cell immunity is impaired in foals during the first three months of life. In contrast, neonatal basophils are potent interleukin-4 (IL-4) producers. Th...

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Detalles Bibliográficos
Autores principales:	Wagner, Bettina, Perkins, Gillian, Babasyan, Susanna, Freer, Heather, Keggan, Alison, Goodman, Laura B., Glaser, Amy, Torsteinsdóttir, Sigurbjorg, Svansson, Vilhjálmur, Björnsdóttir, Sigríður
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207648/ https://www.ncbi.nlm.nih.gov/pubmed/28045974 http://dx.doi.org/10.1371/journal.pone.0169072

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