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Validation of Immune Cell Modules in Multicellular Transcriptomic Data
Numerous gene signatures, or modules have been described to evaluate the immune cell composition in transcriptomes of multicellular tissue samples. However, significant diversity in module gene content for specific cell types is associated with heterogeneity in their performance. In order to rank mo...
Autores principales: | Pollara, Gabriele, Murray, Matthew J., Heather, James M., Byng-Maddick, Rachel, Guppy, Naomi, Ellis, Matthew, Turner, Carolin T., Chain, Benjamin M., Noursadeghi, Mahdad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207692/ https://www.ncbi.nlm.nih.gov/pubmed/28045996 http://dx.doi.org/10.1371/journal.pone.0169271 |
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