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2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways

This study was to explore the mechanisms underlying 1,2-dichloroethane (1,2-DCE) induced brain edema by focusing on alteration of matrix metalloproteinase-2 (MMP-2) in rat astrocytes induced by 2-chloroethanol (2-CE), an intermediate metabolite of 1,2-DCE in vivo. Protein and mRNA levels of MMP-2, a...

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Detalles Bibliográficos
Autores principales:	Sun, Qi, Liao, Yingjun, Wang, Tong, Tang, Hongge, Wang, Gaoyang, Zhao, Fenghong, Jin, Yaping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209348/ https://www.ncbi.nlm.nih.gov/pubmed/28101000 http://dx.doi.org/10.3389/fnins.2016.00593

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