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Elastase-Induced Parenchymal Disruption and Airway Hyper Responsiveness in Mouse Precision Cut Lung Slices: Toward an Ex vivo COPD Model

Background: COPD is a progressive lung disease characterized by emphysema and enhanced bronchoconstriction. Current treatments focused on bronchodilation can delay disease progression to some extent, but recovery or normalization of loss of lung function is impossible. Therefore, novel therapeutic t...

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Detalles Bibliográficos
Autores principales:	Van Dijk, Eline M., Culha, Sule, Menzen, Mark H., Bidan, Cécile M., Gosens, Reinoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209351/ https://www.ncbi.nlm.nih.gov/pubmed/28101062 http://dx.doi.org/10.3389/fphys.2016.00657

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