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Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation

Na(+)K(+)2Cl(−) co-transporters (NKCCs) effect the electroneutral movement of Na(+)-K(+) and 2Cl(−) ions across the plasma membrane of vertebrate cells. There are two known NKCC isoforms, NKCC1 (Slc12a2) and NKCC2 (Slc12a1). NKCC1 is a ubiquitously expressed transporter involved in cell volume regul...

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Detalles Bibliográficos
Autores principales:	Singh, Richa, Kursan, Shams, Almiahoub, Mohamed Y., Almutairi, Mohammed M., Garzón-Muvdi, Tomás, Alvarez-Leefmans, Francisco J., Di Fulvio, Mauricio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209364/ https://www.ncbi.nlm.nih.gov/pubmed/28101499 http://dx.doi.org/10.3389/fcell.2016.00150

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