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The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability

The cystic fibrosis transmembrane conductance regulator (CFTR) is responsible for the disease cystic fibrosis (CF). It is a membrane protein belonging to the ABC transporter family functioning as a chloride/anion channel in epithelial cells around the body. There are over 1500 mutations that have be...

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Detalles Bibliográficos
Autores principales: Meng, Xin, Clews, Jack, Kargas, Vasileios, Wang, Xiaomeng, Ford, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209436/
https://www.ncbi.nlm.nih.gov/pubmed/27734094
http://dx.doi.org/10.1007/s00018-016-2386-8