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Basosquamous carcinoma: appearance and reality

Basosquamous carcinoma (BsC) is a controversial entity and both a diagnostic and therapeutic challenge. BsC has mixed histopathological characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). BCC and SCC display characteristic histopathology and behaviour; on the other...

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Autores principales: Anand, Rakesh L., Collins, Damian, Chapman, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209554/
https://www.ncbi.nlm.nih.gov/pubmed/28058108
http://dx.doi.org/10.1093/omcr/omw095
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author Anand, Rakesh L.
Collins, Damian
Chapman, Anna
author_facet Anand, Rakesh L.
Collins, Damian
Chapman, Anna
author_sort Anand, Rakesh L.
collection PubMed
description Basosquamous carcinoma (BsC) is a controversial entity and both a diagnostic and therapeutic challenge. BsC has mixed histopathological characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). BCC and SCC display characteristic histopathology and behaviour; on the other hand, BsC is a rare tumour, which has variable morphology and displays less predictable behaviour. An early diagnosis of BsC is important due to the particularly aggressive nature of the tumour, the increased likelihood of recurrence and the potential for metastasis. Here, we present a case of BsC presenting as an extensive ulcer on the back. The case highlights the aggressive nature of the tumour and variation in appearance. It is important for all clinicians to be aware of this diagnosis so that the urgency of adequate biopsy in specialist clinics is not underestimated.
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spelling pubmed-52095542017-01-05 Basosquamous carcinoma: appearance and reality Anand, Rakesh L. Collins, Damian Chapman, Anna Oxf Med Case Reports Case Report Basosquamous carcinoma (BsC) is a controversial entity and both a diagnostic and therapeutic challenge. BsC has mixed histopathological characteristics of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). BCC and SCC display characteristic histopathology and behaviour; on the other hand, BsC is a rare tumour, which has variable morphology and displays less predictable behaviour. An early diagnosis of BsC is important due to the particularly aggressive nature of the tumour, the increased likelihood of recurrence and the potential for metastasis. Here, we present a case of BsC presenting as an extensive ulcer on the back. The case highlights the aggressive nature of the tumour and variation in appearance. It is important for all clinicians to be aware of this diagnosis so that the urgency of adequate biopsy in specialist clinics is not underestimated. Oxford University Press 2017-01-03 /pmc/articles/PMC5209554/ /pubmed/28058108 http://dx.doi.org/10.1093/omcr/omw095 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Anand, Rakesh L.
Collins, Damian
Chapman, Anna
Basosquamous carcinoma: appearance and reality
title Basosquamous carcinoma: appearance and reality
title_full Basosquamous carcinoma: appearance and reality
title_fullStr Basosquamous carcinoma: appearance and reality
title_full_unstemmed Basosquamous carcinoma: appearance and reality
title_short Basosquamous carcinoma: appearance and reality
title_sort basosquamous carcinoma: appearance and reality
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209554/
https://www.ncbi.nlm.nih.gov/pubmed/28058108
http://dx.doi.org/10.1093/omcr/omw095
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