The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure

Histone acetylation has been linked to cardiac hypertrophy and heart failure. However, the pathological implications of changes in histone methylation and the effects of interventions with histone methyltransferase inhibitors for heart failure have not been fully clarified. Here, we focused on H3K9m...

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Detalles Bibliográficos
Autores principales: Ono, Tomohiko, Kamimura, Naomi, Matsuhashi, Tomohiro, Nagai, Toshihiro, Nishiyama, Takahiko, Endo, Jin, Hishiki, Takako, Nakanishi, Tsuyoshi, Shimizu, Noriaki, Tanaka, Hirotoshi, Ohta, Shigeo, Suematsu, Makoto, Ieda, Masaki, Sano, Motoaki, Fukuda, Keiichi, Kaneda, Ruri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209701/
https://www.ncbi.nlm.nih.gov/pubmed/28051130
http://dx.doi.org/10.1038/srep39752

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