KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis

Current guidelines lack comprehensive information on the metastatic site-specific role of KRAS mutation in lung adenocarcinoma (LADC). We investigated the effect of KRAS mutation on overall survival (OS) in this setting. In our retrospective study, 500 consecutive Caucasian metastatic LADC patients...

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Detalles Bibliográficos
Autores principales: Lohinai, Zoltan, Klikovits, Thomas, Moldvay, Judit, Ostoros, Gyula, Raso, Erzsebet, Timar, Jozsef, Fabian, Katalin, Kovalszky, Ilona, Kenessey, István, Aigner, Clemens, Renyi-Vamos, Ferenc, Klepetko, Walter, Dome, Balazs, Hegedus, Balazs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209707/
https://www.ncbi.nlm.nih.gov/pubmed/28051122
http://dx.doi.org/10.1038/srep39721

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