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Progressive induction of hepatocyte progenitor cells in chronically injured liver
Differentiated epithelial cells show substantial lineage plasticity upon severe tissue injuries. In chronically injured mouse livers, part of hepatocytes become Sry-HMG box containing 9 (Sox9) (+) epithelial cell adhesion molecule (−) hepatocyte nuclear factor 4 α (+) biphenotypic hepatocytes. Howev...
Autores principales: | Tanimizu, Naoki, Ichinohe, Norihisa, Yamamoto, Masahiro, Akiyama, Haruhiko, Nishikawa, Yuji, Mitaka, Toshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209740/ https://www.ncbi.nlm.nih.gov/pubmed/28051157 http://dx.doi.org/10.1038/srep39990 |
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