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Progressive induction of hepatocyte progenitor cells in chronically injured liver

Differentiated epithelial cells show substantial lineage plasticity upon severe tissue injuries. In chronically injured mouse livers, part of hepatocytes become Sry-HMG box containing 9 (Sox9) (+) epithelial cell adhesion molecule (−) hepatocyte nuclear factor 4 α (+) biphenotypic hepatocytes. Howev...

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Detalles Bibliográficos
Autores principales: Tanimizu, Naoki, Ichinohe, Norihisa, Yamamoto, Masahiro, Akiyama, Haruhiko, Nishikawa, Yuji, Mitaka, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209740/
https://www.ncbi.nlm.nih.gov/pubmed/28051157
http://dx.doi.org/10.1038/srep39990

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