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Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

While distinct stem cell phenotypes follow global changes in chromatin marks, single-cell chromatin technologies are unable to resolve or predict stem cell fates. We propose the first such use of optical high content nanoscopy of histone epigenetic marks (epi-marks) in stem cells to classify emergen...

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Detalles Bibliográficos
Autores principales: Kim, Joseph J., Bennett, Neal K., Devita, Mitchel S., Chahar, Sanjay, Viswanath, Satish, Lee, Eunjee A., Jung, Giyoung, Shao, Paul P., Childers, Erin P., Liu, Shichong, Kulesa, Anthony, Garcia, Benjamin A., Becker, Matthew L., Hwang, Nathaniel S., Madabhushi, Anant, Verzi, Michael P., Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209743/
https://www.ncbi.nlm.nih.gov/pubmed/28051095
http://dx.doi.org/10.1038/srep39406