Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition

Branched-chain amino acids (BCAAs) are essential amino acids for mammals and play key roles in the regulation of protein metabolism. However, the effect of BCAA deficiency on protein metabolism in skeletal muscle in vivo remains unclear. Here we generated mice with lower BCAA concentrations by speci...

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Detalles Bibliográficos
Autores principales: Ishikawa, Takuya, Kitaura, Yasuyuki, Kadota, Yoshihiro, Morishita, Yukako, Ota, Miki, Yamanaka, Fumiya, Xu, Minjun, Ikawa, Masahito, Inoue, Naokazu, Kawano, Fuminori, Nakai, Naoya, Murakami, Taro, Miura, Shinji, Hatazawa, Yukino, Kamei, Yasutomi, Shimomura, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209746/
https://www.ncbi.nlm.nih.gov/pubmed/28051178
http://dx.doi.org/10.1038/srep39825

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